PGLYRP1

Across TCGA patient cohorts, PGLYRP1 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PGLYRP1-associated genes across cancer lineages are MIR5091, LSP1P3, and OR52Z1. Each is linked with PGLYRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGLYRP1-to-partner and partner-to-PGLYRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5091 grouped by PGLYRP1-low versus PGLYRP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP1→partner) and Y-score (partner→PGLYRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5091 →	+0.733	+2.923	<.001	.001	3	1
COAD	LSP1P3 →	+1.151	+5.207	<.001	<.001	3	1
COAD	OR52Z1 →	+0.084	+5.332	<.001	.002	3	1
LUSC	RNU6-1204P →	+0.569	+5.337	<.001	.006	3	1
COAD	TXNL4AP1 →	+0.293	+3.951	<.001	.005	3	1
COAD	RNU6-1304P →	+0.599	+4.308	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

MIR5091 by PGLYRP1 expression — UCEC

Explore this box plot interactively →