PGLYRP1

Across TCGA cell cohorts, PGLYRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,370 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PGLYRP1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Negative regulation of DNA-templated transcription, elongation, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with PGLYRP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PGLYRP1-to-partner and partner-to-PGLYRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by PGLYRP1-low versus PGLYRP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP1→partner) and Y-score (partner→PGLYRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.182	+0.134	.003	.001	3	12
SOFT_TISSUE	Negative regulation of DNA-templated transcription, elongation →	+0.106	+0.191	<.001	<.001	3	12
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.128	+0.098	<.001	.003	3	12
STOMACH	Positive regulation of T-helper 17 cell lineage commitment →	+0.149	+0.188	.002	<.001	3	11
BONE	Microtubule anchoring →	+0.072	+0.100	.001	.007	3	11
OESOPHAGUS	Calcium-independent cell-matrix adhesion →	+0.152	+0.210	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,370 associations by consensus.

Pre-mRNA catabolic process by PGLYRP1 expression — BONE

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