PGK2

Across TCGA patient cohorts, PGK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,317 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PGK2-associated GO terms across cancer lineages are Cellular respiration, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Endoplasmic reticulum organization. Each is linked with PGK2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PGK2-to-partner and partner-to-PGK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by PGK2-low versus PGK2-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGK2→partner) and Y-score (partner→PGK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	Cellular respiration →	+0.020	+0.063	<.001	.001	3	12
STAD	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.052	+0.097	<.001	<.001	3	11
STAD	Endoplasmic reticulum organization →	+0.056	+0.091	<.001	<.001	3	11
STAD	Protein localization to chromosome →	+0.030	+0.067	<.001	<.001	3	11
STAD	Ribosome assembly →	+0.053	+0.083	<.001	<.001	3	11
STAD	Protein localization to mitochondrion →	+0.049	+0.087	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,317 associations by consensus.

Cellular respiration by PGK2 expression — READ

Explore this box plot interactively →