PGK2

Across TCGA patient cohorts, PGK2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,987 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PGK2-associated genes across cancer lineages are PGK1, SPAG4, and CA9. Each is linked with PGK2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PGK2-to-partner and partner-to-PGK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGK2 versus PGK1 in HNSC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGK2→partner) and Y-score (partner→PGK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PGK1 →	+1.055	+0.721	.009	.003	3	9
UCEC	SPAG4 →	+1.049	+0.366	.001	<.001	3	5
PDAC	CA9 →	+2.029	+0.463	<.001	<.001	3	4
UCEC	HILPDA →	+1.069	+0.352	.001	.002	2	5
HNSC	SNAPC1 →	+0.870	+0.611	.001	.009	3	4
HNSC	ENO1 →	+1.120	+0.622	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,987 associations by consensus.

PGK2 vs PGK1 — HNSC

Explore this scatter interactively →