PGK2

Across TCGA cell cohorts, PGK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 207 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PGK2-associated GO terms across cancer lineages are Golgi vesicle transport, Retrograde transport, vesicle recycling within Golgi, and Insulin secretion involved in cellular response to glucose stimulus. Each is linked with PGK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PGK2-to-partner and partner-to-PGK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by PGK2-low versus PGK2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGK2→partner) and Y-score (partner→PGK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Golgi vesicle transport →	+0.050	+0.029	<.001	.007	3	5
LUNG_NSCLC_LUSC	Retrograde transport, vesicle recycling within Golgi →	+0.113	+0.024	<.001	.004	3	3
LUNG_SCLC	Insulin secretion involved in cellular response to glucose stimulus →	+0.146	+0.031	<.001	.003	3	3
LUNG_NSCLC_LUSC	Secondary alcohol metabolic process →	+0.078	+0.037	.001	.005	3	2
LUNG_NSCLC_LUSC	Positive regulation of calcium ion transmembrane transport →	-0.096	-0.036	.002	.009	3	2
LUNG_NSCLC_LUSC	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell →	-0.726	-0.028	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

Golgi vesicle transport by PGK2 expression — LUNG_SCLC

Explore this box plot interactively →