PGGHG

Across TCGA patient cohorts, PGGHG protein abundance is significantly associated with the RNA expression of many other genes, with 10,747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PGGHG-associated genes across cancer lineages are CENPM, E2F1, and LMNB1. Each is linked with PGGHG in more than 3 cancer types. Because this analysis shows association rather than direction, both PGGHG-to-partner and partner-to-PGGHG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGGHG versus CENPM in OV, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGGHG→partner) and Y-score (partner→PGGHG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CENPM →	-0.886	-0.738	.001	<.001	3	4
GBM	E2F1 →	-0.890	-0.325	<.001	.002	3	4
GBM	LMNB1 →	-0.929	-0.357	<.001	<.001	3	4
LUAD	NLRP6 →	+0.580	+0.220	<.001	.006	3	4
GBM	KIF4A →	-0.862	-0.434	.002	.001	3	4
LSCC	TRAP1 →	-0.600	-0.328	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,747 associations by consensus.

PGGHG vs CENPM — OV

Explore this scatter interactively →