PGBD5

Across TCGA pan-cancer cohorts, PGBD5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PGBD5 data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PGBD5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PGBD5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, CCRCC, and GBM are the cancer types where PGBD5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	1.000	0.892	.023	10	view →
CCRCC	DFS	Median	III,IV	0.409	0.771	.023	2	view →
GBM	OS	Quartile	All	0.925	0.722	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

PGBD5–LSCC (DFS)

Open the LSCC breakdown →