PGBD4P8

Across TCGA patient cohorts, PGBD4P8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,710 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PGBD4P8-associated GO terms across cancer lineages are Macromolecule methylation, Intraciliary anterograde transport, and Regulation of DNA methylation-dependent heterochromatin formation. Each is linked with PGBD4P8 in more than 10 cancer types. Because this analysis shows association rather than direction, both PGBD4P8-to-partner and partner-to-PGBD4P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by PGBD4P8-low versus PGBD4P8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD4P8→partner) and Y-score (partner→PGBD4P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Macromolecule methylation →	+0.086	+0.084	<.001	.001	3	11
STAD	Intraciliary anterograde transport →	+0.064	+0.051	<.001	.001	3	10
STAD	Regulation of DNA methylation-dependent heterochromatin formation →	+0.071	+0.064	<.001	.001	3	9
STAD	Organelle disassembly →	+0.104	+0.047	<.001	<.001	3	9
STAD	DNA-templated transcription elongation →	+0.106	+0.047	<.001	.001	3	9
STAD	Protein K48-linked ubiquitination →	+0.108	+0.086	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,710 associations by consensus.

Macromolecule methylation by PGBD4P8 expression — STAD

Explore this box plot interactively →