PGBD4P8

Across TCGA pan-cancer cohorts, PGBD4P8 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PGBD4P8 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher PGBD4P8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PGBD4P8 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

CESC, THYM, and BRCA are the cancer types where PGBD4P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	II,III,IV	0.091	0.830	<.001	108	view →
THYM	OS	Tertile	All	0.736	0.974	.006	63	view →
BRCA	DFS	Quartile	III,IV	0.954	0.854	.011	48	view →
STAD	OS	Tertile	All	0.240	0.552	.009	36	view →
LGG	OS	Tertile	All	0.312	0.512	<.001	36	view →
OV	DFS	Tertile	All	0.238	0.383	.049	24	view →
LUAD	DFS	Tertile	All	0.761	0.317	.014	18	view →
KIRP	DFS	Tertile	All	1.000	0.696	.040	12	view →
PAAD	OS	Tertile	II,III,IV	0.283	0.565	.002	9	view →
READ	DFS	Tertile	IV	0.409	0.656	.018	9	view →
GBM	OS	Tertile	All	0.353	0.238	.036	9	view →
LIHC	OS	Tertile	II,III,IV	0.944	0.690	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PGBD4P8–CESC (OS)

Open the CESC breakdown →