PGBD4

Across TCGA patient cohorts, PGBD4 mutation is significantly associated with the RNA expression of many other genes, with 2,921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGBD4-associated genes across cancer lineages are RNU6-1052P, KRTAP20-3, and TRAJ12. Each is linked with PGBD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGBD4-to-partner and partner-to-PGBD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1052P grouped by PGBD4-low versus PGBD4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD4→partner) and Y-score (partner→PGBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-1052P →	+0.288	+7.954	<.001	.008	3	2
UCEC	KRTAP20-3 →	+0.050	+3.645	<.001	<.001	3	2
UCEC	TRAJ12 →	+0.505	+1.643	<.001	.001	3	2
UCEC	IGHD2-2 →	+1.279	+2.065	<.001	<.001	3	2
UCEC	LINC02528 →	+0.209	+1.807	.003	<.001	3	2
LUAD	MTCYBP17 →	+0.058	+5.912	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,921 associations by consensus.

RNU6-1052P by PGBD4 expression — HNSC

Explore this box plot interactively →