PGBD4

Across TCGA cell cohorts, PGBD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,121 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGBD4-associated GO terms across cancer lineages are mRNA splice site recognition, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with PGBD4 in more than 12 cancer types. Because this analysis shows association rather than direction, both PGBD4-to-partner and partner-to-PGBD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by PGBD4-low versus PGBD4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGBD4→partner) and Y-score (partner→PGBD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.160	+0.759	<.001	<.001	3	13
URINARY_TRACT	Promoter clearance during DNA-templated transcription →	+0.112	+0.378	.003	.006	3	13
URINARY_TRACT	RNA polymerase II promoter clearance →	+0.112	+0.378	.003	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Microtubule nucleation →	+0.108	+0.738	<.001	<.001	3	13
SOFT_TISSUE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.130	+0.330	<.001	<.001	3	12
SOFT_TISSUE	Heterochromatin formation →	+0.077	+0.357	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,121 associations by consensus.

mRNA splice site recognition by PGBD4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →