PGAP6

Across TCGA cell cohorts, PGAP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,377 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PGAP6-associated GO terms across cancer lineages are Lysosome organization, Lytic vacuole organization, and Protein localization to plasma membrane. Each is linked with PGAP6 in more than 13 cancer types. Because this analysis shows association rather than direction, both PGAP6-to-partner and partner-to-PGAP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosome organization grouped by PGAP6-low versus PGAP6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP6→partner) and Y-score (partner→PGAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Lysosome organization →	+0.059	+1.107	.001	<.001	3	14
URINARY_TRACT	Lytic vacuole organization →	+0.059	+1.107	.001	<.001	3	14
BONE	Protein localization to plasma membrane →	+0.102	+1.039	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement →	-0.092	-1.017	<.001	.002	3	12
SKIN	Organophosphate ester transport →	+0.040	+1.301	<.001	<.001	3	12
BONE	Cytosolic transport →	+0.074	+0.875	.005	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,377 associations by consensus.

Lysosome organization by PGAP6 expression — URINARY_TRACT

Explore this box plot interactively →