PGAP6

Across TCGA cell cohorts, PGAP6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,172 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGAP6-associated genes across cancer lineages are MCM10, GOLGA3, and NCAPG. Each is linked with PGAP6 in more than 5 cancer types. Because this analysis shows association rather than direction, both PGAP6-to-partner and partner-to-PGAP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGAP6 versus MCM10 in BLOOD_Leukemia, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP6→partner) and Y-score (partner→PGAP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MCM10 →	-0.868	-0.859	<.001	<.001	3	6
LIVER	GOLGA3 →	-0.720	-0.722	.002	.001	3	6
LIVER	NCAPG →	-1.296	-0.830	.006	.003	3	5
URINARY_TRACT	PSMC3IP →	-1.073	-0.755	.004	.001	3	5
BLOOD_Leukemia	CENPO →	-0.825	-0.800	<.001	<.001	3	5
CNS	RAD51 →	-0.838	-0.523	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,172 associations by consensus.

PGAP6 vs MCM10 — BLOOD_Leukemia

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