PGAP3

Across TCGA patient cohorts, PGAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PGAP3-associated proteins across cancer lineages are NFKB2, GRB7, and UBASH3B. Each is linked with PGAP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both PGAP3-to-partner and partner-to-PGAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGAP3 versus NFKB2 in LSCC, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP3→partner) and Y-score (partner→PGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NFKB2 →	-0.361	-0.730	<.001	<.001	3	5
BRCA	GRB7 →	+1.242	+1.797	<.001	<.001	3	5
CCRCC	UBASH3B →	-0.425	-0.341	.002	.002	3	5
BRCA	PIP4K2B →	+0.442	+1.051	<.001	<.001	3	5
BRCA	ERBB2 →	+0.759	+0.877	<.001	<.001	3	5
LSCC	AMPD3 →	-0.367	-0.682	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,360 associations by consensus.

PGAP3 vs NFKB2 — LSCC

Explore this scatter interactively →