PGAP3

Across TCGA patient cohorts, PGAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PGAP3-associated genes across cancer lineages are CERK, GSS, and MYOM1. Each is linked with PGAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGAP3-to-partner and partner-to-PGAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGAP3 versus CERK in LUAD, with a Pearson correlation of -0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP3→partner) and Y-score (partner→PGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CERK →	-0.446	-0.701	<.001	.004	3	1
LUAD	GSS →	+0.512	+0.670	<.001	.006	3	1
LUAD	MYOM1 →	-0.780	-0.685	.002	.005	3	1
LUAD	ATG4A →	+0.592	+0.697	<.001	.004	3	1
LUAD	PBDC1 →	+0.606	+0.370	<.001	.001	3	1
LUAD	FNDC3A →	-0.427	-0.686	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

PGAP3 vs CERK — LUAD

Explore this scatter interactively →