PGAP3

Across TCGA cell cohorts, PGAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,202 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PGAP3-associated GO terms across cancer lineages are Flagellated sperm motility, Cilium movement involved in cell motility, and Sperm motility. Each is linked with PGAP3 in more than 12 cancer types. Because this analysis shows association rather than direction, both PGAP3-to-partner and partner-to-PGAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Flagellated sperm motility grouped by PGAP3-low versus PGAP3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP3→partner) and Y-score (partner→PGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.105	-1.154	.002	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.101	-1.003	.003	.005	3	13
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.105	-1.154	.002	.001	3	13
URINARY_TRACT	Glycerophospholipid metabolic process →	+0.046	+1.071	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.106	-1.328	.002	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.106	-1.328	.002	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,202 associations by consensus.

Flagellated sperm motility by PGAP3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →