PGAP2

Across TCGA cell cohorts, PGAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,471 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PGAP2-associated GO terms across cancer lineages are Telomere tethering at nuclear periphery, Cilium or flagellum-dependent cell motility, and Cilium-dependent cell motility. Each is linked with PGAP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both PGAP2-to-partner and partner-to-PGAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere tethering at nuclear periphery grouped by PGAP2-low versus PGAP2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAP2→partner) and Y-score (partner→PGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Telomere tethering at nuclear periphery →	+0.145	+1.181	.004	.001	2	14
LIVER	Cilium or flagellum-dependent cell motility →	-0.099	-0.777	.001	.009	3	13
LIVER	Cilium-dependent cell motility →	-0.099	-0.777	.001	.009	3	13
LIVER	Flagellated sperm motility →	-0.120	-0.777	<.001	.009	3	12
LIVER	Sperm motility →	-0.120	-0.777	<.001	.009	3	12
STOMACH	Long-chain fatty acid metabolic process →	-0.114	-1.049	.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,471 associations by consensus.

Telomere tethering at nuclear periphery by PGAP2 expression — STOMACH

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