PGAM2

Across TCGA patient cohorts, PGAM2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,615 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PGAM2-associated genes across cancer lineages are FLNC, MYL3, and RND2. Each is linked with PGAM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PGAM2-to-partner and partner-to-PGAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGAM2 versus FLNC in HNSC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGAM2→partner) and Y-score (partner→PGAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FLNC →	+1.551	+1.058	<.001	<.001	3	4
HNSC	MYL3 →	+1.250	+1.038	<.001	<.001	3	4
BRCA	RND2 →	+0.905	+0.588	.005	.007	3	3
OV	RGN →	+1.010	+1.243	<.001	.001	3	3
HNSC	CSDC2 →	+0.669	+1.104	<.001	<.001	3	3
OV	LINC02308 →	+1.422	+1.688	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,615 associations by consensus.

PGAM2 vs FLNC — HNSC

Explore this scatter interactively →