PFN2

Across TCGA patient cohorts, PFN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,389 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PFN2-associated proteins across cancer lineages are NFKB1, BAG2, and RAB6B. Each is linked with PFN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PFN2-to-partner and partner-to-PFN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFN2 versus NFKB1 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFN2→partner) and Y-score (partner→PFN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NFKB1 →	-0.264	-0.871	.001	.001	3	6
BRCA	BAG2 →	+0.617	+1.337	<.001	<.001	3	6
LSCC	RAB6B →	+0.975	+1.036	<.001	<.001	3	5
CCRCC	PLOD2 →	+0.974	+0.740	<.001	<.001	3	5
LUAD	UCHL1 →	+1.171	+1.233	<.001	<.001	3	5
OV	CBX2 →	+1.097	+0.856	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,389 associations by consensus.

PFN2 vs NFKB1 — GBM

Explore this scatter interactively →