PFN1P10

Across TCGA pan-cancer cohorts, PFN1P10 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated PFN1P10 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher PFN1P10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PFN1P10 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

ACC, STAD, and ESCA are the cancer types where PFN1P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.075	0.635	<.001	63	view →
STAD	DFS	Tertile	III,IV	0.269	0.547	.005	60	view →
ESCA	OS	Tertile	IV	0.143	0.650	.004	54	view →
READ	DFS	Tertile	III,IV	0.294	0.773	.001	48	view →
GBM	OS	Tertile	All	0.112	0.421	.017	18	view →
MESO	DFS	Tertile	III,IV	0.194	0.385	.038	9	view →
HNSC	OS	Tertile	All	0.478	0.721	.038	6	view →
UCEC	DFS	Tertile	All	0.819	0.902	.037	6	view →
BLCA	OS	Tertile	All	1.000	0.657	.027	6	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

PFN1P10–ACC (DFS)

Open the ACC breakdown →