PFKFB2

Across TCGA patient cohorts, PFKFB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,803 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PFKFB2-associated proteins across cancer lineages are PFKFB2_S493, PFKFB2_S466, and PFKFB2_S483. Each is linked with PFKFB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PFKFB2-to-partner and partner-to-PFKFB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PFKFB2 versus PFKFB2_S493 in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PFKFB2→partner) and Y-score (partner→PFKFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PFKFB2_S493 →	+1.104	+1.008	<.001	<.001	3	10
BRCA	PFKFB2_S466 →	+0.729	+0.901	<.001	<.001	3	7
BRCA	PFKFB2_S483 →	+1.059	+0.790	<.001	<.001	3	6
LSCC	AKR7A3 →	+0.916	+0.454	<.001	<.001	3	5
UCEC	BPNT1 →	+0.401	+1.097	<.001	<.001	3	5
LSCC	RPRD2 →	+0.271	+0.415	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,803 associations by consensus.

PFKFB2 vs PFKFB2_S493 — BRCA

Explore this scatter interactively →