PFDN5

Across TCGA patient cohorts, PFDN5 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. CESC shows the largest number of these associations.

The most reproducible PFDN5-associated genes across cancer lineages are RPL23P4, RAB42P1, and LINC02467. Each is linked with PFDN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PFDN5-to-partner and partner-to-PFDN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23P4 grouped by PFDN5-low versus PFDN5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN5→partner) and Y-score (partner→PFDN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPL23P4 →	+0.145	+4.653	<.001	.004	3	2
CESC	RAB42P1 →	+0.182	+4.193	.001	.009	3	2
CESC	LINC02467 →	+0.066	+5.837	<.001	.001	3	2
COAD	RNU6-694P →	+0.443	+5.893	<.001	.002	3	2
CESC	OR7G3 →	+0.060	+4.669	<.001	.007	3	1
CESC	KRTAP4-5 →	+0.081	+4.539	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

RPL23P4 by PFDN5 expression — CESC

Explore this box plot interactively →