PFDN5

Across TCGA cell cohorts, PFDN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,499 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PFDN5-associated GO terms across cancer lineages are Proton-transporting two-sector ATPase complex assembly, Regulation of protein import into nucleus, and Pre-mRNA catabolic process. Each is linked with PFDN5 in more than 12 cancer types. Because this analysis shows association rather than direction, both PFDN5-to-partner and partner-to-PFDN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton-transporting two-sector ATPase complex assembly grouped by PFDN5-low versus PFDN5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PFDN5→partner) and Y-score (partner→PFDN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Proton-transporting two-sector ATPase complex assembly →	+0.113	+0.832	<.001	<.001	3	13
PANCREAS	Regulation of protein import into nucleus →	-0.126	-0.730	<.001	<.001	3	11
BONE	Pre-mRNA catabolic process →	-0.227	-0.576	<.001	.002	3	11
BONE	Viral translational termination-reinitiation →	-0.105	-0.757	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of PERK-mediated unfolded protein response →	-0.107	-0.543	<.001	<.001	3	10
CNS	Regulation of protein localization to endoplasmic reticulum →	-0.120	-0.629	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,499 associations by consensus.

Proton-transporting two-sector ATPase complex assembly by PFDN5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →