PF4

Across TCGA patient cohorts, PF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,467 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PF4-associated proteins across cancer lineages are PPBP, SLC4A1, and EPB41. Each is linked with PF4 in more than 8 cancer types. Because this analysis shows association rather than direction, both PF4-to-partner and partner-to-PF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PF4 versus PPBP in OV, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PF4→partner) and Y-score (partner→PF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPBP →	+1.220	+0.554	<.001	<.001	3	9
CCRCC	SLC4A1 →	+1.211	+0.862	<.001	<.001	3	8
GBM	EPB41 →	+0.663	+1.053	<.001	<.001	3	7
CCRCC	SPTB →	+1.135	+0.863	<.001	<.001	3	7
OV	HBQ1 →	+0.838	+0.408	.001	.005	3	7
CCRCC	EPB42 →	+1.045	+0.815	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,467 associations by consensus.

PF4 vs PPBP — OV

Explore this scatter interactively →