PF4

Across TCGA cell cohorts, PF4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PF4-associated genes across cancer lineages are CXorf51A. Each is linked with PF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PF4-to-partner and partner-to-PF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51A grouped by PF4-low versus PF4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PF4→partner) and Y-score (partner→PF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CXorf51A →	+0.082	+5.472	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CXorf51A by PF4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →