PEX5L-AS2

Across TCGA pan-cancer cohorts, PEX5L-AS2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of PEX5L-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where PEX5L-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types PEX5L-AS2 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and HNSC are the cancer types where PEX5L-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PEX5L-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.113	<.001	7	view →
KICH	All	All	−0.206	.001	5	view →
HNSC	All	II,III,IV	−0.050	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

PEX5L-AS2–KIRC

Open the KIRC breakdown →