PEX3

Across TCGA patient cohorts, PEX3 protein abundance is significantly associated with the RNA expression of many other genes, with 20,859 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PEX3-associated genes across cancer lineages are MRPL18, AEBP1, and ACAT2. Each is linked with PEX3 in more than 5 cancer types. Because this analysis shows association rather than direction, both PEX3-to-partner and partner-to-PEX3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX3 versus MRPL18 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX3→partner) and Y-score (partner→PEX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPL18 →	+0.585	+0.307	.001	.004	3	5
CCRCC	AEBP1 →	-1.117	-0.228	.003	.007	2	6
OV	ACAT2 →	+0.832	+0.337	<.001	.001	3	4
BRCA	MTFR2 →	+0.703	+0.323	<.001	<.001	2	5
UCEC	LRP1 →	-0.673	-0.351	.003	.001	3	4
BRCA	HSPG2 →	-0.789	-0.286	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,859 associations by consensus.

PEX3 vs MRPL18 — OV

Explore this scatter interactively →