PEX13

Across TCGA cell cohorts, PEX13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,692 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PEX13-associated GO terms across cancer lineages are Protein import into peroxisome matrix, docking, Regulation of chromatin organization, and Golgi organization. Each is linked with PEX13 in more than 13 cancer types. Because this analysis shows association rather than direction, both PEX13-to-partner and partner-to-PEX13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein import into peroxisome matrix, docking grouped by PEX13-low versus PEX13-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX13→partner) and Y-score (partner→PEX13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Protein import into peroxisome matrix, docking →	+0.115	+0.606	<.001	<.001	3	14
LIVER	Regulation of chromatin organization →	+0.090	+0.704	.004	.007	3	10
LARGE_INTESTINE	Golgi organization →	+0.056	+0.532	<.001	<.001	2	11
LUNG_SCLC	Negative regulation of transcription by RNA polymerase I →	+0.097	+0.401	.002	.006	3	10
KIDNEY	Stress granule assembly →	+0.067	+0.326	.002	<.001	3	9
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.041	+0.624	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,692 associations by consensus.

Protein import into peroxisome matrix, docking by PEX13 expression — SKIN

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