PEX11G

Across TCGA patient cohorts, PEX11G mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PEX11G-associated genes across cancer lineages are RNA5SP534, ELMO2P1, and SERPINA9. Each is linked with PEX11G in more than 1 cancer types. Because this analysis shows association rather than direction, both PEX11G-to-partner and partner-to-PEX11G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP534 grouped by PEX11G-low versus PEX11G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX11G→partner) and Y-score (partner→PEX11G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP534 →	+0.329	+3.242	.001	.007	3	1
UCEC	ELMO2P1 →	+0.158	+2.847	.004	.004	3	1
UCEC	SERPINA9 →	+0.238	+3.681	.001	.003	3	1
UCEC	RN7SL498P →	+0.172	+3.133	.002	.009	3	1
UCEC	MIR548AW →	+0.345	+4.437	<.001	.005	3	1
UCEC	MIR4675 →	+0.434	+3.484	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

RNA5SP534 by PEX11G expression — UCEC

Explore this box plot interactively →