PEX11G

Across TCGA pan-cancer cohorts, PEX11G RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated PEX11G data layer compared with 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PEX11G RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PEX11G expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, KIRP, and UCEC are the cancer types where PEX11G RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.704	0.541	<.001	124	view →
KIRP	OS	Tertile	All	0.758	0.509	<.001	112	view →
UCEC	DFS	Median	All	0.888	0.786	<.001	74	view →
BRCA	OS	Tertile	All	0.957	0.903	.002	44	view →
LIHC	DFS	Median	All	0.401	0.237	.001	44	view →
LGG	DFS	Median	All	0.666	0.807	<.001	37	view →
MESO	OS	Tertile	All	0.490	0.275	.011	36	view →
SARC	OS	Quartile	All	0.871	0.624	<.001	31	view →
READ	DFS	Median	All	0.881	0.377	<.001	31	view →
COAD	DFS	Median	All	0.849	0.708	.002	17	view →
SCLC	DFS	Median	All	0.396	0.152	.006	15	view →
DLBC	DFS	Tertile	II,III,IV	0.447	1.000	.018	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

PEX11G–KIRC (DFS)

Open the KIRC breakdown →