PEX11B

Across TCGA patient cohorts, PEX11B mutation is significantly associated with the RNA expression of many other genes, with 2,212 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PEX11B-associated genes across cancer lineages are RN7SL787P, LCN9, and RNA5SP137. Each is linked with PEX11B in more than 1 cancer types. Because this analysis shows association rather than direction, both PEX11B-to-partner and partner-to-PEX11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL787P grouped by PEX11B-low versus PEX11B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX11B→partner) and Y-score (partner→PEX11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL787P →	+0.254	+5.148	<.001	.008	3	1
SKCM	LCN9 →	+0.131	+5.080	<.001	.004	3	1
BRCA	RNA5SP137 →	+0.253	+5.045	.003	.009	3	1
BRCA	SNORD115-9 →	+0.225	+8.057	<.001	.005	3	1
BRCA	MIR595 →	+0.346	+5.610	.004	.004	3	1
BRCA	TRGJ2 →	+1.124	+6.442	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,212 associations by consensus.

RN7SL787P by PEX11B expression — BRCA

Explore this box plot interactively →