PEX11A

Across TCGA patient cohorts, PEX11A protein abundance is significantly associated with the RNA expression of many other genes, with 5,097 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PEX11A-associated genes across cancer lineages are GNB3, TOB1, and MPC2. Each is linked with PEX11A in more than 2 cancer types. Because this analysis shows association rather than direction, both PEX11A-to-partner and partner-to-PEX11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEX11A versus GNB3 in BRCA, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX11A→partner) and Y-score (partner→PEX11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GNB3 →	-0.591	-1.090	.004	.001	3	3
BRCA	TOB1 →	+1.178	+0.922	<.001	.004	3	3
LSCC	MPC2 →	+0.738	+0.688	<.001	<.001	3	3
LSCC	FAM160B1 →	+0.492	+0.646	<.001	<.001	3	3
OV	RAB4A →	+0.691	+0.992	.003	.007	3	3
GBM	LMBRD1 →	+0.805	+0.534	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,097 associations by consensus.

PEX11A vs GNB3 — BRCA

Explore this scatter interactively →