PEX11A

Across TCGA patient cohorts, PEX11A mutation is significantly associated with the RNA expression of many other genes, with 1,025 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PEX11A-associated genes across cancer lineages are LINC02684, DPPA2, and RNU6-207P. Each is linked with PEX11A in more than 2 cancer types. Because this analysis shows association rather than direction, both PEX11A-to-partner and partner-to-PEX11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02684 grouped by PEX11A-low versus PEX11A-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX11A→partner) and Y-score (partner→PEX11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02684 →	+0.743	+6.584	<.001	.001	3	3
UCEC	DPPA2 →	+0.887	+3.595	.001	.003	3	2
LUAD	RNU6-207P →	+0.452	+5.343	<.001	.006	3	2
LUAD	H4C7 →	+0.126	+5.044	.003	.009	3	2
SKCM	HMGN2P9 →	+0.171	+3.953	<.001	.005	3	2
STAD	RNU6-169P →	+0.544	+5.026	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,025 associations by consensus.

LINC02684 by PEX11A expression — LUAD

Explore this box plot interactively →