PEX11A

Across TCGA cell cohorts, PEX11A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PEX11A-associated genes across cancer lineages are MYF6, OR1L6, and OR11A1. Each is linked with PEX11A in more than 1 cancer types. Because this analysis shows association rather than direction, both PEX11A-to-partner and partner-to-PEX11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by PEX11A-low versus PEX11A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEX11A→partner) and Y-score (partner→PEX11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MYF6 →	+0.019	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR1L6 →	+0.036	+6.022	<.001	.001	3	1
LARGE_INTESTINE	OR11A1 →	+0.021	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TIFAB →	+0.006	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MYF6 by PEX11A expression — LARGE_INTESTINE

Explore this box plot interactively →