PER3

Across TCGA cell cohorts, PER3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,395 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PER3-associated GO terms across cancer lineages are Protein stabilization, Positive regulation of post-translational protein modification, and Caveolin-mediated endocytosis. Each is linked with PER3 in more than 9 cancer types. Because this analysis shows association rather than direction, both PER3-to-partner and partner-to-PER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by PER3-low versus PER3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PER3→partner) and Y-score (partner→PER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein stabilization →	+0.051	+1.748	.001	.001	3	10
LUNG_SCLC	Positive regulation of post-translational protein modification →	+0.060	+1.570	.003	.005	3	10
LUNG_NSCLC_LUSC	Caveolin-mediated endocytosis →	+0.213	+1.981	<.001	.001	3	9
BONE	Positive regulation of steroid biosynthetic process →	+0.149	+1.615	<.001	<.001	3	9
BREAST	Regulation of cell cycle G1/S phase transition →	+0.062	+1.357	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of protein modification by small protein conjugation or removal →	+0.061	+1.676	.002	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,395 associations by consensus.

Protein stabilization by PER3 expression — STOMACH

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