PELO

Across TCGA patient cohorts, PELO RNA expression is significantly associated with the protein abundance of many other proteins, with 10,247 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PELO-associated proteins across cancer lineages are HTRA3, PLOD2, and SPARC. Each is linked with PELO in more than 4 cancer types. Because this analysis shows association rather than direction, both PELO-to-partner and partner-to-PELO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PELO versus HTRA3 in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PELO→partner) and Y-score (partner→PELO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HTRA3 →	+0.737	+0.465	<.001	<.001	3	5
PDAC	PLOD2 →	+0.994	+0.355	<.001	<.001	3	5
PDAC	SPARC →	+0.539	+0.316	<.001	.001	3	4
PDAC	IGFBP4 →	+0.521	+0.351	<.001	<.001	3	4
GBM	IKBIP →	+0.600	+0.317	<.001	<.001	3	4
PDAC	LOXL2 →	+0.694	+0.327	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,247 associations by consensus.

PELO vs HTRA3 — COAD

Explore this scatter interactively →