PELO

Across TCGA pan-cancer cohorts, PELO RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PELO data layer compared with 6 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PELO RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PELO expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

BRCA, KIRC, and UVM are the cancer types where PELO RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.868	0.937	<.001	70	view →
KIRC	DFS	Tertile	All	0.722	0.530	<.001	62	view →
UVM	DFS	Quartile	III,IV	0.234	0.903	.001	49	view →
MESO	OS	Quartile	All	0.381	0.728	.002	46	view →
KIRP	DFS	Tertile	II,III,IV	0.151	0.612	.004	41	view →
READ	DFS	Median	All	0.876	0.556	.002	30	view →
LIHC	OS	Tertile	All	0.585	0.798	<.001	30	view →
HNSC	OS	Quartile	All	0.458	0.806	.002	29	view →
LUAD	DFS	Tertile	All	0.743	0.848	.005	28	view →
THCA	OS	Median	II,III,IV	0.563	1.000	.006	21	view →
LGG	OS	Tertile	All	0.806	0.927	<.001	19	view →
COAD	DFS	Tertile	II,III,IV	0.291	0.785	.002	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PELO–BRCA (DFS)

Open the BRCA breakdown →