PELO

Across TCGA cell cohorts, PELO RNA expression is significantly associated with the go_rna of many other GO terms, with 4,824 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PELO-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, no-go decay, Positive regulation of protein exit from endoplasmic reticulum, and Regulation of protein exit from endoplasmic reticulum. Each is linked with PELO in more than 16 cancer types. Because this analysis shows association rather than direction, both PELO-to-partner and partner-to-PELO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, no-go decay grouped by PELO-low versus PELO-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PELO→partner) and Y-score (partner→PELO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Nuclear-transcribed mRNA catabolic process, no-go decay →	+0.140	+0.824	<.001	<.001	3	17
SOFT_TISSUE	Positive regulation of protein exit from endoplasmic reticulum →	+0.100	+0.826	<.001	.003	3	14
LIVER	Regulation of protein exit from endoplasmic reticulum →	+0.143	+0.906	.005	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	COPII-coated vesicle cargo loading →	+0.093	+0.965	.002	.003	3	13
SKIN	Regulation of intracellular transport →	+0.074	+1.028	<.001	<.001	3	12
SOFT_TISSUE	Maintenance of protein localization in organelle →	+0.108	+0.746	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,824 associations by consensus.

Nuclear-transcribed mRNA catabolic process, no-go decay by PELO expression — LIVER

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