PELI2

Across TCGA patient cohorts, PELI2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,701 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PELI2-associated genes across cancer lineages are DDX21, SQLE, and RHBDD1. Each is linked with PELI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PELI2-to-partner and partner-to-PELI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PELI2 versus DDX21 in UCEC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI2→partner) and Y-score (partner→PELI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DDX21 →	-0.689	-0.480	<.001	<.001	3	2
UCEC	SQLE →	-0.823	-0.570	.004	.008	3	2
UCEC	RHBDD1 →	-0.389	-0.460	.004	.007	3	2
UCEC	CHCHD4P2 →	-0.466	-0.354	.002	.008	3	2
UCEC	MTND4LP7 →	+0.540	+0.349	.009	.008	3	2
UCEC	MIR5094 →	-1.019	-0.469	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,701 associations by consensus.

PELI2 vs DDX21 — UCEC

Explore this scatter interactively →