PELI2

Across TCGA patient cohorts, PELI2 mutation is significantly associated with the RNA expression of many other genes, with 3,744 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PELI2-associated genes across cancer lineages are STOML2, SSR3, and CACYBP. Each is linked with PELI2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PELI2-to-partner and partner-to-PELI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STOML2 grouped by PELI2-low versus PELI2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI2→partner) and Y-score (partner→PELI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STOML2 →	+0.380	+2.777	.001	<.001	3	3
UCEC	SSR3 →	+0.355	+1.375	.002	.008	3	3
UCEC	CACYBP →	+0.584	+2.010	<.001	<.001	3	3
UCEC	TCP1 →	+0.480	+1.999	<.001	<.001	3	3
UCEC	HACL1 →	+0.538	+2.273	<.001	<.001	3	3
UCEC	RTN3 →	+0.327	+2.332	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,744 associations by consensus.

STOML2 by PELI2 expression — UCEC

Explore this box plot interactively →