PELI2

Across TCGA cell cohorts, PELI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,105 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PELI2-associated GO terms across cancer lineages are Aerobic respiration, Copper ion export, and Regulation of cytoplasmic translation. Each is linked with PELI2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PELI2-to-partner and partner-to-PELI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by PELI2-low versus PELI2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI2→partner) and Y-score (partner→PELI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Aerobic respiration →	+0.094	+1.241	.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Copper ion export →	-0.138	-1.207	.005	.001	3	10
OESOPHAGUS	Regulation of cytoplasmic translation →	+0.100	+2.140	.002	.001	3	9
BLOOD_Leukemia	Regulation of mRNA stability →	+0.030	+1.119	.001	.001	3	9
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.373	<.001	.002	3	9
LIVER	Peptidyl-threonine phosphorylation →	+0.084	+1.879	.007	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,105 associations by consensus.

Aerobic respiration by PELI2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →