Across TCGA cell cohorts, PELI1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PELI1-associated genes across cancer lineages are IQCF5, SLC38A8, and OR52B2. Each is linked with PELI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PELI1-to-partner and partner-to-PELI1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PELI1→partner) and Y-score (partner→PELI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	IQCF5 →	+0.056	+5.357	<.001	.003	3	1
BLOOD_Lymphoma	SLC38A8 →	+0.109	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	OR52B2 →	+0.021	+4.714	.006	.002	3	1
LARGE_INTESTINE	TBC1D3 →	+0.080	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PELI1 survival (RNA) · tumor vs normal (RNA) · all PELI1 data types