PELATON

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PELATON RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated PELATON data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PELATON RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PELATON expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.

UVM, ACC, and BRCA are the cancer types where PELATON RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileII,III,IV0.3360.809<.001104view →
ACCDFSTertileAll0.2640.715.00172view →
BRCAOSTertileIV0.3910.951<.00137view →
LGGOSMedianAll0.3720.522<.00134view →
COADOSQuartileAll0.7110.899.00432view →
LAMLDFSQuartileAll0.2920.578.00332view →
GBMOSQuartileAll0.2970.552<.00130view →
KIRPDFSMedianAll0.9660.854<.00127view →
UCSOSTertileIII,IV0.3010.693.00918view →
STADOSMedianIV0.1610.509.00612view →
SKCMOSQuartileIV0.4620.850.00512view →
THYMDFSQuartileAll0.5920.884.0189view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration