PECR

Across TCGA pan-cancer cohorts, PECR mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PECR data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PECR mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PECR expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where PECR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.989	0.133	.020	25	view →
PDAC	DFS	Tertile	III,IV	1.000	0.613	.016	5	view →
UCEC	OS	Tertile	All	1.000	0.898	.045	4	view →
HNSC	OS	Median	All	0.910	0.798	.039	2	view →
LUAD	OS	Quartile	III,IV	0.377	0.879	.020	2	view →
LSCC	OS	Median	All	0.709	0.866	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PECR–CCRCC (OS)

Open the CCRCC breakdown →