PECR

Across TCGA pan-cancer cohorts, PECR RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of PECR’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where PECR RNA is repressed in tumor relative to normal tissue. In most cancer types PECR is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, COAD, and LUSC are the cancer types where PECR tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PECR RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.498	<.001	8	view →
COAD	Female	IV	−1.620	<.001	8	view →
LUSC	Female	II,III,IV	−1.652	<.001	7	view →
LUAD	Female	II,III,IV	−0.939	<.001	7	view →
BRCA	All	All	−0.723	<.001	6	view →
READ	All	II,III,IV	−0.745	.005	4	view →
CHOL	Male	All	−1.665	<.001	3	view →
ESCA	All	All	+1.085	.010	2	view →
PRAD	All	All	−0.311	.019	2	view →
KIRC	All	All	−0.213	.029	2	view →
HNSC	Male	III,IV	+0.435	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

PECR–KICH

Open the KICH breakdown →