PECR

Across TCGA patient cohorts, PECR protein abundance is significantly associated with the RNA expression of many other genes, with 12,451 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PECR-associated genes across cancer lineages are TMEM169, MEX3A, and ABCC6P2. Each is linked with PECR in more than 4 cancer types. Because this analysis shows association rather than direction, both PECR-to-partner and partner-to-PECR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PECR versus TMEM169 in PDAC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PECR→partner) and Y-score (partner→PECR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TMEM169 →	+0.813	+0.645	<.001	<.001	3	5
BRCA	MEX3A →	-1.070	-0.424	.001	<.001	3	5
CCRCC	ABCC6P2 →	+0.650	+0.427	<.001	<.001	3	5
GBM	ABI3BP →	+0.922	+0.327	.001	.004	3	5
LSCC	DKC1 →	-0.581	-0.262	<.001	<.001	3	4
LSCC	SERPINA1 →	+1.551	+0.435	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,451 associations by consensus.

PECR vs TMEM169 — PDAC

Explore this scatter interactively →