PEBP4

Across TCGA pan-cancer cohorts, PEBP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PEBP4 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PEBP4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PEBP4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, HNSC, and UCEC are the cancer types where PEBP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.930	0.698	.002	40	view →
HNSC	DFS	Quartile	II,III,IV	0.282	1.000	.008	22	view →
UCEC	DFS	Tertile	All	0.531	0.939	.008	18	view →
LUAD	OS	Median	II,III,IV	0.857	1.000	.003	17	view →
PDAC	OS	Quartile	All	0.419	0.776	.018	15	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PEBP4–CCRCC (DFS)

Open the CCRCC breakdown →