PEBP4

Across TCGA patient cohorts, PEBP4 protein abundance is significantly associated with the RNA expression of many other genes, with 16,583 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PEBP4-associated genes across cancer lineages are TEK, PTPRB, and HDC. Each is linked with PEBP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both PEBP4-to-partner and partner-to-PEBP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PEBP4 versus TEK in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PEBP4→partner) and Y-score (partner→PEBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TEK →	+0.800	+0.682	<.001	<.001	3	4
CCRCC	PTPRB →	+0.673	+0.367	.006	.001	3	4
BRCA	HDC →	+1.454	+0.636	.003	<.001	3	4
BRCA	ABCA8 →	+0.760	+0.428	<.001	<.001	3	4
LUAD	PGM5 →	+0.662	+0.461	<.001	<.001	3	4
LSCC	PBK →	-1.003	-0.473	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,583 associations by consensus.

PEBP4 vs TEK — BRCA

Explore this scatter interactively →