PEBP1P3

Across TCGA pan-cancer cohorts, PEBP1P3 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of PEBP1P3’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where PEBP1P3 RNA is repressed in tumor relative to normal tissue. In most cancer types PEBP1P3 is over-expressed in tumor, although a few such as LUSC and THCA show the opposite, repressed pattern.

LUSC, THCA, and BRCA are the cancer types where PEBP1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PEBP1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	III,IV	−0.265	.001	5	view →
THCA	Female	All	−0.134	.001	2	view →
BRCA	All	III,IV	−0.069	.005	2	view →
STAD	Male	IV	−0.665	.025	1	view →
LUAD	Male	III,IV	−0.260	.001	1	view →
KICH	All	II,III,IV	−0.118	.036	1	view →
KIRC	All	All	+0.047	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

PEBP1P3–LUSC

Open the LUSC breakdown →