PEBP1

Across TCGA pan-cancer cohorts, PEBP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PEBP1 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher PEBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PEBP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and LUAD are the cancer types where PEBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.873	0.634	<.001	32	view →
CCRCC	OS	Median	IV	0.785	0.123	.009	29	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.320	.006	20	view →
UCEC	OS	Median	II,III,IV	0.522	1.000	.003	4	view →
HNSC	DFS	Tertile	III,IV	0.895	0.715	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PEBP1–PDAC (DFS)

Open the PDAC breakdown →